Performance of Rapid Tests and Algorithms for HIV Screening in Abidjan, Ivory Coast
Performance of Rapid Tests and Algorithms for HIV Screening in Abidjan, Ivory Coast
Blog Article
Seven rapid diagnosis tests (RDTs) of HIV were evaluated by a panel group who collected serum samples from patients in Abidjan (HIV-1 = 203, HIV-2 = 25, HIV-dual = 25, HIV = 305).Kit performances were recorded after the reference techniques (enzyme-linked wahl power grip clippers immunosorbent assay).The following RDTs showed a sensitivity of 100% and a specificity higher than 99%: Determine, Oraquick, SD Bioline, BCP, and Stat-Pak.
These kits were used to establish infection screening strategies.The combination with 2 or 3 of these tests in series or parallel algorithms showed that series combinations with 2 tests (Oraquick and Bioline) and 3 tests (Determine, BCP, and Stat-Pak) gave the best performances (sensitivity, specificity, positive predictive value, and negative predictive value of 100%).However, the combination with 2 tests appeared to be more onerous than the combination with 3 tests.
The combination with Determine, BCP, and Stat-Pak tests serving as a tiebreaker could be an chondroprotec for dogs alternative to the HIV/AIDS serological screening in Abidjan.